An Introduction to Pharmaceutical Formulation by A. G. Fishburn

By A. G. Fishburn

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And to aqueous cream a n d ointment bases. P. includes a monograph for Bentonite M a g m a which is a 5 per cent suspension for dispensing purposes. I n cream bases, bentonite is used in various concentrations ; if it is the main thickener in a hydrophilic base, u p to 20 per cent m a y be required but smaller proportions are used when in combination with oil-in-water emulsifying agents. Bentonite is safe for oral and external application but, like talc, it should be heat-sterilized before application to broken skin since it may contain bacterial spores.

Includes a monograph for Bentonite M a g m a which is a 5 per cent suspension for dispensing purposes. I n cream bases, bentonite is used in various concentrations ; if it is the main thickener in a hydrophilic base, u p to 20 per cent m a y be required but smaller proportions are used when in combination with oil-in-water emulsifying agents. Bentonite is safe for oral and external application but, like talc, it should be heat-sterilized before application to broken skin since it may contain bacterial spores.

Pharmacol. 1960, 12, 154 237 (Cellulose derivatives). and CHAPTER 4 SURFACE-ACTIVE AGENTS ONE of the most interesting developments in formulation over the past twenty years has been the marked increase in the use of surfaceactive agents. Prior to this period only a few of these substances, such as soap, quillaia, cholesterol and lecithin, were available for pharmaceutical use, but several are now defined in official monographs and more still have been investigated and are commercially available in medicinal quality.

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